concept

INFLAMMATORY DISEASES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INFLAMMATORY DISEASES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections

0Hypotheses

2Analyses

0Outgoing

28Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	INFLAMMATORY DISEASES

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    INFLAMMATORY_DISEASES["INFLAMMATORY DISEASES"]
    Organelle_specific_autophagy["Organelle-specific autophagy"] -->|"involved_in"| INFLAMMATORY_DISEASES
    Organelle_specific_Autophagy["Organelle-specific Autophagy"] -->|"involved_in"| INFLAMMATORY_DISEASES
    IL1B["IL1B"] -->|"causes"| INFLAMMATORY_DISEASES
    NLRP3_Inflammasome["NLRP3 Inflammasome"] -->|"involved_in"| INFLAMMATORY_DISEASES
    NLRP3_INFLAMMASOME["NLRP3 INFLAMMASOME"] -->|"involved_in"| INFLAMMATORY_DISEASES
    Organelle_Specific_Autophagy["Organelle-Specific Autophagy"] -->|"involved_in"| INFLAMMATORY_DISEASES
    Berberine["Berberine"] -->|"treats"| INFLAMMATORY_DISEASES

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (28)

Source	Relation	Type	Str
Organelle-specific autophagy	associated_with	process	0.95
Organelle-specific autophagy	involved_in	process	0.95
Organelle-specific Autophagy	involved_in	process	0.95
IL1B	causes	gene	0.90
NLRP3 Inflammasome	involved_in	protein	0.90
Organelle-specific Autophagy	treats	process	0.90
Organelle-Specific Autophagy	involved_in	process	0.90
Berberine	treats	compound	0.90
organelle quality control	therapeutic_target	process	0.90
NLRP3 INFLAMMASOME	involved_in	protein	0.90
TNF-α	associated_with	protein	0.90
Nlrp3 Inflammasome	involved_in	protein	0.90
Organelle Dysfunction	contributes_to	phenotype	0.88
PANoptosis	associated_with	process	0.88
Organelle-Specific Autophagy	protects_against	process	0.85
TET2 Dysregulation	contributes_to	phenotype	0.85
Nlrp Sensor Proteins	associated_with	protein	0.85
Mitophagy	protects_against	process	0.85
Tet2 Dysregulation	causes	mechanism	0.82
self-DNA activation	causes	phenotype	0.80
Phytochemicals	protects_against	compound	0.80
berberine	treats	drug	0.80
NLRP Inflammasome Inhibitors	treats	drug	0.80
Organelle-Specific Autophagy	treats	process	0.80
NF-κB Inhibition	treats	mechanism	0.80
ANXA1	therapeutic_target	protein	0.80
TRIM45	associated_with	protein	0.75
cGAS-STING pathway	causes	pathway	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (2)

Scientific analyses that reference this entity

What determines organelle-specific autophagy selectivity in neurodegenerative di

neurodegeneration | 2026-04-08 | 0 hypotheses

How do different organelle-specific autophagy pathways coordinate during neurode

neurodegeneration | 2026-04-07 | 0 hypotheses

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

INFLAMMATORY DISEASES

Understanding Entity Pages

Wiki Pages (20)

Section 148: Advanced Nutritional Biochemistry in CBS/PSP

Paraventricular Hypothalamic Nucleus (PVN) Neurons

Neuroinflammation-Mitochondria Crosstalk Pathway

Necroptotic Neurons

Psychobiotic Therapy for Neurodegenerative Diseases

cynata-therapeutics

Melanotrophs

Johnson & Johnson

MAPK9 Gene

Neuroinflammation Microglia

SERPINA3 Gene — Alpha-1 Antichymotrypsin in Neurodegeneration

DNA Sensing Pathways in Neurodegeneration

IL32

CTS Gene - Cathepsin S

IL3 (Interleukin 3)

ASC (PYCARD)

Neuroinflammation in Parkinson's Disease

Regeneron Pharmaceuticals

Viral Involvement in Neurodegeneration Pathway

IL27 — Interleukin 27